U.S. publishers should complete an application form and send it to the U.S. ISSN Center together with a representation of the serial (either a sample issue, or a photocopy of the cover, title page (if present), masthead, publisher information, and any other pages giving information about the serial).
There is no charge for the assignment of the ISSN, or for the use of an ISSN once assigned.
The Library of Congress incurs substantial costs to staff and maintain the U.S. ISSN Center. Additionally, the Library of Congress is assessed a considerable fee to belong to the ISSN Network.).