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Systematic Reviews and Related Evidence Syntheses

About This Guide

Evidence synthesis is a type of secondary research created for use in evidence-based practice that combines information from a comprehensive range of sources to guide decisions and policies on specific issues.

  • Researchers use established methods and unbiased information gathering practices that strives to include all high quality research.
  • Systematic reviews represent one key type of evidence synthesis.

 This guide supports researchers of all experience levels and disciplines in understanding and conducting systematic and structured literature reviews and syntheses.

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Types of Reviews

Over twenty review types exist. Key types are defined in the tabs above.  

  • See the "Proposal" tab for more help determining the best review type for your project.

Recommended reading: 

Narrative/Literature Reviews

Identify, evaluate, and summarize the existing body of work produced by researchers, scholars, and practitioners on a particular topic (Fink, 2019). A literature review can be a standalone publication (journal article or book chapter) or can provide context for a new research study by serving as its introduction. 


The research question is broad and methods are not described. Other members of the traditional review family include:

  • Critical review
  • Narrative review
  • Narrative summary
  • State of the art review
  • Integrative review or synthesis (common in nursing, these may describe some methods)

Systematic Reviews

“A form of research synthesis that seeks to systematically search for, appraise and synthesize research evidence, using strategies to limit bias often adhering to guidelines on the conduct of a review.” (Booth et al., 2022). Generally speaking, a systematic review includes the following steps.

  • Formulate a well-defined research question using a specified framework 
  • Define inclusion/exclusion criteria for studies 
  • Develop & implement search strategy 
  • Select your studies (screen & analyze) 
  • Critically appraise selected studies (risk of bias assessment) 
  • Synthesize results 
  • Report findings

How you conduct each step and report findings depends on the guidelines you choose to follow. 
See the Standards & Guidelines page for more information. 


The research question for a systematic review is narrow and stated within a specific framework (PICO, PCC, PEO, etc.), methods are clearly described, and included studies are appraised. Other members of the systematic review family include but are not limited to:

  • Comparative effectiveness review
  • Diagnostic systematic or diagnostic test accuracy review
  • Prevalence and/or incidence review
  • Etiology and/or risk review 
  • Meta-analysis

Scoping Reviews

Typically assess the potential size and scope of available research literature on a topic (Grant & Booth, 2009). Arksey & O'Malley (2005) propose a framework for conducting a scoping study which includes: 

  • Identifying the research question 
  • Identifying relevant studies 
  • Study selection 
  • Charting the data 
  • Collating, summarizing and reporting the results 

The research question is broad, methods are described, and in depth data extraction is performed.

JBI: What are scoping reviews? (6 minutes)

Mapping Reviews

Examine a typically broad topic area to map out and categorize existing literature from which to propose future primary research or systematic review(s). (Grant & Booth, 2009; Sutton et al., 2019)

The research question is broader than for a scoping review, less in depth analysis. 


Research questions for scoping and mapping reviews are broad and stated within frameworks, and methods are described. 

  • Evidence gap maps are also part of the big picture review family. 

Meta-analyses

Statistically combine results of multiple studies. They usually start with a systematic review and can be performed when multiple studies address the same question and measure the same outcome using similar or comparable methods (Booth et al., 2022). 

Review type Purpose Search Coding/Appraisal Synthesis
Narrative review Topic overview Varies in scope
Not transparent
Varies
Not described
Qualitative,
sometimes unbalanced
Scoping/Mapping Description of evidence base
(Exploratory)
Varies in scope
Documented
Categories only
No appraisal
Visual (tables or "maps")
Systematic review In-depth synthesis to answer a specific question Comprehensive
Documented
In-depth coding
Required quality appraisal 
Qualitative
Meta-analysis Numerical synthesis on studies on same specific question Comprehensive
Documented
In-depth coding
Required quality appraisal
Quantitative

Visit the Duke University Medical Center Library page to view a comprehensive comparison table of 14 review types.  

Phases of a Review Project

Circular diagram of the PIECES Review Cycle, consisting of eight interconnected puzzle-like segments labeled: Proposal, Protocol, Production, Paper, Preservation, Promotion, Impact, and Update. At the center are the core review actions: Plan, Identify, Evaluate, Extract, Combine, Explain, Summarize, Share. The cycle represents the continuous, systematic process of managing a review project.

The image illustrates the PIECES Review Cycle

This 8-phase framework guiding the lifecycle of a review project starts with Proposal (feasibility), it progresses through Protocol (methods), Production (preliminary findings), Paper (publication), Preservation (sharing), Promotion (stakeholder engagement), Impact tracking, and finally Update criteria.

Each of these phases involves eight core processes: Plan, Identify, Evaluate, Extract, Combine, Explain, Summarize, and Share, ensuring a systematic and comprehensive approach throughout the review project's life.


PIECCESS Framework was summarized fromFoster MJ and Jewell ST (Eds.) (2022) Piecing Together Systematic Reviews and Other Evidence Syntheses. (Medical Library Association Books Series) Lanham: Rowman & Littlefield. Dec 2022.